Find a Clinical Trial | American Lung Association

HARBOR Study

The HARBOR Study is evaluating the safety and effectiveness of a potential medicine (HZN-825) that may slow disease progression in participants with idiopathic pulmonary fibrosis (IPF).

IMPALA2

To discover whether molgramostim (inhaled GM-CSF) is safe to take and can help to reduce the symptoms of (autoimmune pulmonary alveolar proteinosis ) aPAP.

Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH)

The ACRC network is studying whether having regular telehealth appointments with a pharmacist using a study provided tablet or a person’s smart phone or computer will help adolescents and young adults with asthma to gain control of asthma symptoms and improve inhaler effectiveness.

KEAPSAKE

A Phase 2 Randomized, Multicenter, Double-Blind Study of the Glutaminase Inhibitor Telaglenastat with Pembro and CTX Versus Placebo with Pembro and CTX in 1L, Metastatic KEAP1/NRF2-Mutated, Nonsquamous NSCLC

LUNG STAAR

The purpose of this research is to offer patients with centrally located early-stage non-small cell lung cancer (NSCLC) who are NOT candidates for surgery the opportunity to receive stereotactic body radiation therapy (SBRT).

MAHALE

This is a multicentre, randomised, double-blind, parallel-group, placebo-controlled, 52 week Phase III study to test the hypothesis that benralizumab will reduce exacerbation rates compared with placebo on top of standard-of-care therapy in adult patients with non-cystic fibrosis bronchiectasis with eosinophilic inflammation (NCFB+EI).

Optimizing self-management COPD treatment through the American Lung Association Helpline

The current study will test the feasibility of using an engineering-inspired study design to identify effective COPD self-management treatment components.

Phase 2, Open-Label, Study of the Combination of RMC-4630 and Sotorasib for Non-Small Cell Lung Cancer

The purpose of this study is to evaluate the antitumor effects of sotorasib and RMC-4630 subjects with KRASG12C mutant NSCLC that have not been exposed to prior therapy with KRASG12C inhibitors and/or SHP2 inhibitors.

RELIANCE

RELIANCE is multi-site pragmatic study to compare long-term roflumilast use with long-term azithromycin use in people who have COPD with chronic bronchitis who have been hospitalized in the past year.

Sarilumab in Patients With Glucocorticoid-Dependent Sarcoidosis

The purpose of this study is to compare the effectiveness and the safety of sarilumab in patients with glucocorticoid-dependent sarcoidosis.

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