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United to BEAT Lung Cancer

It starts with biomarker education, awareness and testing. Learn how early diagnosis, biomarker testing and targeted treatment can save lives.
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About every two minutes, someone in the U.S. is diagnosed with lung cancer. While lung cancer is the leading cause of cancer deaths in the U.S., we have seen incredible progress in the survival rate thanks in part to biomarker testing and new treatment availability.

For most, biomarker testing is now considered a standard part of lung cancer diagnosis, especially for individuals with non–small cell lung cancer (NSCLC). Unfortunately, not enough people are getting biomarker testing, especially within historically underrepresented communities. Everyone diagnosed with lung cancer deserves the chance to receive the treatment that is most likely to work for their specific type of cancer. 

Access to biomarker testing is not just a medical issue; it’s an equity issue. No matter where someone lives, what insurance they have, or what their background is, they should have the same opportunity to benefit from the most advanced treatments available. Ensuring universal access means giving every patient the best possible chance at longer survival, better quality of life, and more treatment options, all of which can empower individuals in their efforts to beat lung cancer. 

What is Biomarker Testing?

Biomarker testing, also called molecular testing or genomic testing, analyzes the tumor’s DNA and the levels of certain proteins. This deeper look can reveal specific genetic changes, or biomarkers, that help guide treatment decisions. 

Biomarker testing is the only way to identify the genetic and molecular tumor features that guide personalized treatment decisions. Without it, individuals may miss out on targeted therapies, immunotherapies, or clinical trials that could significantly improve their outcomes. If you’ve been diagnosed with lung cancer, understanding the power of biomarker testing can be one of the most important steps in shaping your treatment path.

Health disparities persist when it comes to lung cancer care and biomarker testing.

Lung cancer affects Black communities, particularly Black men, differently than their white counterparts. There’s a need to increase biomarker testing rates in communities most impacted by lung cancer disparities. It’s important to prepare the right questions to ask your doctor from the beginning and to stay involved throughout your treatment plan. 

26% of eligible white patients received biomarker testing compared to 14% of eligible Black patients.

Black individuals are 15% less likely to be diagnosed with lung cancer early, 19% less likely to receive surgical treatment, 11% more likely to not receive any treatment and 1% less likely to survive five years when compared to white individuals.

Black men are 11% more likely to be diagnosed with lung cancer and 9.8% more Black men die from the disease.

Nearly 4 in 10 (38%) Black individuals reported not having discussed their lung cancer risk with a doctor prior to their lung cancer diagnosis and one third did not receive biomarker testing for their lung cancer.

(24%) indicated that their doctor did not recommend biomarker testing for their lung cancer.

Screening and Early Detection Is Key

Diagnosing lung cancer begins at the time of detection through lung cancer screening. Most commonly, doctors suspect somebody might have lung cancer when they see something on an imaging test, such as a CT scan, that looks like it could be a tumor.

Using a low-dose CT (LDCT), an X-ray machine which takes multiple pictures of your lungs, lung cancer can be detected before any symptoms appear and may be easier to treat. 

If you meet the following criteria, you are considered to be at "high risk" for developing lung cancer and screening is recommended:

  • 50-80 years of age (50-77 years of age for Medicare)  
  • Have a 20 pack-year history of smoking (this means 1 pack a day for 20 years, 2 packs a day for 10 years, etc.)
  • AND, currently smoke, or have quit within the last 15 years

How Screening and Biomarker Testing Lead to More Treatment Options

The goal of lung cancer screening is simple: catch lung cancer as early as possible, when it is most treatable and when patients have the greatest number of treatment options. When a low‑dose CT (LDCT) scan finds a possible tumor early, doctors can move quickly to confirm the diagnosis and perform comprehensive biomarker testing during a biopsy.

Biomarker testing examines the tumor’s genetic and molecular features and can identify specific mutations or markers that drive the cancer’s growth. The results help determine whether a patient may benefit from targeted therapy, which are treatments designed to attack cancer cells with those exact mutations. Targeted therapies often work more precisely and may cause fewer side effects than traditional chemotherapy.

Because of this, early detection combined with biomarker testing opens the door to personalized treatment plans, precision medicine, and innovative therapies that may not have been available otherwise. Catching cancer early ensures that people receive treatments tailored to the biology of their cancer, which can lead to better outcomes and more treatment options.

Even if biomarker testing does not reveal a mutation with an approved targeted therapy, there are still important treatment decisions to make. Clinical trials are actively studying new treatments for all types of lung cancer, including cancers without known biomarkers or without currently approved targeted therapies. These studies may offer access to promising therapies that could benefit you. Talk with your doctor about the availability of clinical trials to see if one is right for you. Call the Lung Cancer Helpline if you have questions or are interested in learning more about biomarker testing or lung cancer screening. 

Contact a Lung Health Navigator

Speak to one of our dedicated Lung Health Navigators if you have questions or are interested in learning more about biomarker testing or lung cancer screenings.

What is Your Experience with Lung Cancer and Biomarker Testing?

If you have been diagnosed with lung cancer, biomarker testing can help determine what treatment options would be best for you and your chances to BEAT lung cancer. We're hoping to learn more about people's unique experience with biomarker testing after a lung cancer diagnosis.
Take our survey

Page last updated: June 3, 2026

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