Tobias Martin Hohl, MD, PhD

Research Project:
Understanding the Immune System’s Balancing Act During Co-Infections

Grant Awarded:

Emerging Respiratory Pathogen Award

Research Topic:

immunology immunotherapy

Research Diseases:

pneumonia
respiratory viruses

Every time we breathe, our lungs encounter a variety of airborne microbes, such as viruses and fungi. A key question is how the immune system manages infections with different types of microbes at the same time. During the recent pandemic, secondary fungal infections became a major issue for patients with severe COVID-19. To study this, we developed an experimental model to study immune responses during co-infection with a coronavirus and the mold Aspergillus fumigatus. We will study whether the immune response to coronaviruses affects the antifungal functions of immune cells called myeloid cells, which are critical for clearing fungal infections and ensuring survival. This research will help us better understand the immune system’s balancing act during co-infections and could lead to new treatment strategies.

The Keith R. Ayres Emerging Respiratory Pathogens Award

Page last updated: October 30, 2025

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