COPD-OMA Study logo

Have COPD and allergies? This research study might be for you!

We’re looking for volunteers to take part in a research study testing whether a medication used for asthma and allergic diseases—called omalizumab—could help prevent chronic obstructive pulmonary disease (COPD) flare-ups in people who have allergies.

 

COPD flare-ups can lead to ER visits, hospital stays and serious health setbacks.

If we can reduce these flare-ups, people could breathe easier and live better. You may be able to help us find out.

The trial is conducted by the American Lung Association Airways Clinical Research Centers

What Is the COPD-OMA(lizumab) Study?

Many people with COPD are sensitive to allergens they may have exposure to in their home every day. Researchers want to learn whether treating that allergic component with omalizumab can improve COPD symptoms and reduce flare-ups.

While omalizumab is already FDA-approved for other allergic conditions, this study will help us learn whether it may also help:

  • Reduce COPD flare-ups
  • Improve breathing symptoms and quality of life
  • Support lung function

By participating, you’re playing an important role in shaping future COPD care.

Older man outside in front of flowering tree sneezes into elbow

How to Participate

You Contact Us

Use our site locator to pick and email the site nearest you.

This will make it easy for us to accommodate your schedule for in-person appointments.

Pick a Site

Participation Details

You may qualify if you: 

  • Are over 40 
  • Have been diagnosed with COPD by your healthcare provider 
  • Have a history of flare-ups or ongoing symptoms
  • Currently use inhalers on a daily basis 
  • Are willing to be tested for common indoor allergies

Unfortunately, you will not be able to participate if you:

  • Are on another injected medication for allergies or lung disease 
  • Recently had certain lung surgeries 
  • Are pregnant or breastfeeding
  • Are participating in another study with a drug intervention

The study team will determine if the study is a safe fit for you.

If you qualify for the study, you will:

  • Receive study medication or placebo by injection every 2–4 weeks for 12 months 
  • Continue your current COPD treatments 
  • Attend clinic visits and complete health surveys 
  • Receive close medical monitoring throughout the study 
  • Have a follow-up phone call one month after your last visit

Total time in the study: about 14–16 months

For in-person visits, compensation is available for time and travel.

COPD-OMA is sponsored by the American Lung Association, the National Institutes of Health’s National Institute of Allergy and Infectious Diseases, and Genentech.

Find the Study Site Near You

Enter your state or zip code to find the site closest to your home, office or wherever—totally up to you.

This research has been approved by the Johns Hopkins Institutional Review Board

Protocol: IRB00498976

ClinicalTrials.gov identifier: NCT07059091 

Lead Investigator: Nirupama Putcha


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